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Discovery of benzyl carbamate inhibitors of coronavirus Mpro enzymes from a legacy collection of cysteine protease inhibitors.

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Title: Discovery of benzyl carbamate inhibitors of coronavirus Mpro enzymes from a legacy collection of cysteine protease inhibitors.
Authors: Sá Magalhães Serafim, Mateus1,2,3 (AUTHOR), Kronenberger, Thales4,5 (AUTHOR), Francisco, Karol R.1 (AUTHOR), de Sousa Reis, Erik Vinicius2 (AUTHOR), Gonçalves de Oliveira, Ellen1,2 (AUTHOR), Marcelino e Oliveira, Fernanda Kelly2,3 (AUTHOR), Serraglio Fortes, Isadora1,6,7 (AUTHOR), Maciel Fernandes, Thaís Helena1,8 (AUTHOR), Barbosa da Silva, Elany1 (AUTHOR), Fajtova, Pavla1 (AUTHOR), Skinner, Danielle E.1 (AUTHOR), Syed, Rafay O.1 (AUTHOR), Lage de Siqueira-Neto, Jair1 (AUTHOR), Poso, Antti5,9 (AUTHOR), Fernandes Mota, Bruno Eduardo3 (AUTHOR), Alves Coelho-dos-Reis, Jordana Grazziela2 (AUTHOR), Santos Abrahão, Jônatas2 (AUTHOR), Gonçalves Maltarollo, Vinícius10 (AUTHOR), O'Donoghue, Anthony J.1 (AUTHOR) ajodonoghue@health.ucsd.edu, Caffrey, Conor R.1 (AUTHOR) ccaffrey@health.ucsd.edu
Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2025, Vol. 40 Issue 1, p1-24. 24p.
Database: Academic Search Ultimate
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Description
ISSN:14756366
DOI:10.1080/14756366.2025.2585619