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Elevated mortality and upregulated SARS-CoV-2-associated pathways in innate and adaptive immune cells from individuals with Down syndrome.

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Title: Elevated mortality and upregulated SARS-CoV-2-associated pathways in innate and adaptive immune cells from individuals with Down syndrome.
Authors: Victorino, Daniella Balduino1 (AUTHOR), Malheiros, Jackeline Moraes2 (AUTHOR), Ten-Caten, Felipe3 (AUTHOR), Cardoso Betta, Victor Hugo2 (AUTHOR), Barbosa, Felipe Farinha Saad2 (AUTHOR), Ghneim, Khader3 (AUTHOR), Coirada, Fernanda Caroline3 (AUTHOR), Bruno, Fernanda Romano3 (AUTHOR), de Medeiros, Giuliana Xavier3 (AUTHOR), Silveira, Cassia4 (AUTHOR), Gavegnano, Christina5,6,7,8,9 (AUTHOR), Balderas, Robert10 (AUTHOR), Brandao, Ana Claudia11 (AUTHOR), Yang, Edward12 (AUTHOR), Nakaya, Helder11 (AUTHOR), Wagner, Gabriela A.13 (AUTHOR), Covolan, Luciene2,12 (AUTHOR), Pereira Ribeiro, Susan3 (AUTHOR) susan.pereira.ribeiro@emory.edu
Source: PLoS ONE. 1/5/2026, Vol. 21 Issue 1, p1-14. 14p.
Database: Academic Search Ultimate
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ISSN:19326203
DOI:10.1371/journal.pone.0338519