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Intra-patient neuraminidase mutations in avian H5N1 influenza virus reduce sialidase activity to complement weaker hemagglutinin binding and facilitate human infection.

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Title: Intra-patient neuraminidase mutations in avian H5N1 influenza virus reduce sialidase activity to complement weaker hemagglutinin binding and facilitate human infection.
Authors: Watanabe, Yohei1,2 (AUTHOR) nabe@koto.kpu-m.ac.jp, Ibrahim, Madiha S.3 (AUTHOR), Arai, Yasuha2 (AUTHOR), Kuroda, Daisuke4 (AUTHOR), Elgendy, Emad M.3 (AUTHOR), Nakakita, Shin-ichi5 (AUTHOR), Takeda, Yohei6,7 (AUTHOR), Nghia Bui, Vuong8 (AUTHOR), Ono, Takao9 (AUTHOR), Ushiba, Shota10 (AUTHOR), Daidoji, Tomo2,11 (AUTHOR), Sriwilaijaroen, Nongluk12,13 (AUTHOR), Ogawa, Haruko6 (AUTHOR), Matsumoto, Kazuhiko14 (AUTHOR), Suzuki, Yasuo13 (AUTHOR), Nakaya, Takaaki2 (AUTHOR)
Source: PLoS Pathogens. 1/23/2026, Vol. 22 Issue 1, p1-28. 28p.
Database: Academic Search Ultimate
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ISSN:15537366
DOI:10.1371/journal.ppat.1013863