Study protocol for a multicenter phase II prospective externally controlled non-inferiority trial of hypofractionated re-irradiation in patients with recurrent high-grade glioma (RISinG).

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Title: Study protocol for a multicenter phase II prospective externally controlled non-inferiority trial of hypofractionated re-irradiation in patients with recurrent high-grade glioma (RISinG).
Authors: de Jong, A. M.1,2 (AUTHOR) a.m.dejong-42@umcutrecht.nl, van der Boog, A. T. J.1,2 (AUTHOR), Post, C. C. B.1 (AUTHOR), Cialdella, F.1,2 (AUTHOR), Eekers, D. B. P.3 (AUTHOR), Hendrikse, J.4 (AUTHOR), Kramer, M. C. A.5 (AUTHOR), Lagerwaard, F. J.6 (AUTHOR), van der Meulen, M.7 (AUTHOR), Philippens, M. E. P.1 (AUTHOR), Robe, P. A.2 (AUTHOR), Rozema, T.8 (AUTHOR), de Vos, F. Y. F. L.9 (AUTHOR), Vos-Westerman, J.10 (AUTHOR), van der Weide, H. L.5 (AUTHOR), Wester, G.11 (AUTHOR), Zindler, J.12 (AUTHOR), Snijders, T. J.2 (AUTHOR), Verhoeff, J. J. C.1,6 (AUTHOR)
Source: PLoS ONE. 2/9/2026, Vol. 21 Issue 2, p1-20. 20p.
Database: Academic Search Ultimate
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ISSN:19326203
DOI:10.1371/journal.pone.0342337