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Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies.

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Title: Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies.
Authors: Zhang, Chi1,2 (AUTHOR), Zhu, Yanjing1,2 (AUTHOR), Ai, Luoyan1,2 (AUTHOR), Wang, Jingyuan1,2 (AUTHOR), Yu, Shan1,2 (AUTHOR), Wang, Yichen3 (AUTHOR), Xu, Xiaojing1,2 (AUTHOR), Liu, Mengling1,2 (AUTHOR), Yu, Yiyi1,2 (AUTHOR), Zhu, Mengxuan1,2 (AUTHOR), Liu, Yutong1,2 (AUTHOR), Xu, Zhenghang1,2 (AUTHOR), Zhou, Haojie1,2 (AUTHOR), Li, Huishan1,2 (AUTHOR), Huang, Qihong2 (AUTHOR), Liu, Qing1,2 (AUTHOR) liu.qing@zs-hospital.sh.cn, Peng, Ke1,2 (AUTHOR) peng.ke@zs-hospital.sh.cn, Liu, Tianshu1,2,4,5,6 (AUTHOR) liu.tianshu@zs-hospital.sh.cn
Source: Advanced Science. 2/13/2026, Vol. 13 Issue 9, p1-17. 17p.
Database: Academic Search Ultimate
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ISSN:21983844
DOI:10.1002/advs.202512074