Carba-NAD binding activates SIR2 by reshaping conformational plasticity and rewiring long-range allosteric networks.

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Title: Carba-NAD binding activates SIR2 by reshaping conformational plasticity and rewiring long-range allosteric networks.
Authors: Zhang, Bao-Dan1,2,3 (AUTHOR), Zhao, De-Rui1,2,3 (AUTHOR), Liu, Meng-Ting1,2 (AUTHOR), Yang, Li-Quan1,2,3 (AUTHOR) ylqbioinfo@dali.edu.cn, Sang, Peng1,2,3 (AUTHOR) pengsang@dali.edu.cn
Source: PLoS Computational Biology. 2/20/2026, Vol. 22 Issue 2, p1-19. 19p.
Database: Academic Search Ultimate
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ISSN:1553734X
DOI:10.1371/journal.pcbi.1013966