Synthesis and evaluation of carmofur analogs as antiproliferative agents, inhibitors to the main protease (Mpro) of SARS-CoV-2, and membrane rupture-inducing agents.

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Title: Synthesis and evaluation of carmofur analogs as antiproliferative agents, inhibitors to the main protease (Mpro) of SARS-CoV-2, and membrane rupture-inducing agents.
Authors: Gu, Tiffany1 (AUTHOR), Lu, Amber1 (AUTHOR), Wang, Xina1 (AUTHOR), Brahan, Natalie1 (AUTHOR), Xu, Lexi1 (AUTHOR), Zhang, Leyuan1 (AUTHOR), Su, Kaitlyn1 (AUTHOR), Seow, Kody1 (AUTHOR), Vu, Julia1 (AUTHOR), Luk, Charissa1 (AUTHOR), Lee, Yunseo1 (AUTHOR), Raman, Anirudh1 (AUTHOR), Pazzi, Joseph1,2 (AUTHOR) joey.pazzi@asdrp.org, Njoo, Edward1 (AUTHOR) edward.njoo@asdrp.org
Source: Discover Chemistry. Dec2025, Vol. 2 Issue 1, p1-15. 15p.
Database: Academic Search Ultimate
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DOI:10.1007/s44371-025-00144-9