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An intrinsic loop-mediated structural stability modulating inhibitor potency in the SADS-CoV and SARS-CoV-2 main proteases.

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Title: An intrinsic loop-mediated structural stability modulating inhibitor potency in the SADS-CoV and SARS-CoV-2 main proteases.
Authors: Zeng, Rui1 (AUTHOR), Cui, Shizhan2 (AUTHOR), Xia, Xiaoyan1 (AUTHOR), Huang, Chong1 (AUTHOR), Sun, Jingxuan1 (AUTHOR), Deng, Xinyue1 (AUTHOR), Gui, Qiaoling1 (AUTHOR), Fan, Huahao3 (AUTHOR), Liu, Xiaojuan2 (AUTHOR), Yu, Yang2,4,5 (AUTHOR) yuyang5012@hotmail.com, Yang, Shengyong1 (AUTHOR) yangsy@scu.edu.cn, Lei, Jian1 (AUTHOR) leijian@scu.edu.cn
Source: PLoS Pathogens. 2/24/2026, Vol. 22 Issue 2, p1-23. 23p.
Database: Academic Search Ultimate
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Description
ISSN:15537366
DOI:10.1371/journal.ppat.1013981