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A systematically optimized two-dose differential strategy integrating stable isotope tracing and mass shift defect filtering for reducing false positives in high-resolution mass spectrometry–based drug metabolite profiling.

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Bibliographic Details
Title: A systematically optimized two-dose differential strategy integrating stable isotope tracing and mass shift defect filtering for reducing false positives in high-resolution mass spectrometry–based drug metabolite profiling.
Authors: Lin, Chang-Te1 (AUTHOR), Chiou, Yi-Shiou1,2,3 (AUTHOR), Yang, Ji-Rui4 (AUTHOR), Wang, Jie-Huei5 (AUTHOR), Yen, Meng-Chi6 (AUTHOR), Li, Cai-Rong7 (AUTHOR), Shih, Chia-Lung1,7 (AUTHOR) stone770116@gmail.com
Source: Talanta. Aug2026, Vol. 305, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
Description
ISSN:00399140
DOI:10.1016/j.talanta.2026.129582