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Genome and Transcriptome-Wide Analyses Identify Multiple Candidate Genes and a Significant Polygenic Contribution in Bicuspid Aortic Valve.

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Title: Genome and Transcriptome-Wide Analyses Identify Multiple Candidate Genes and a Significant Polygenic Contribution in Bicuspid Aortic Valve.
Authors: Thériault, Sébastien1 (AUTHOR) scbody@bu.edu, Holdcraft, Jacob A.1,2 (AUTHOR) Holdcraft@hcp.med.harvard.edu, Sharipova, Dinara1,3 (AUTHOR) dinara.sharipova@uni-potsdam.de, Faucherre, Adèle1,4 (AUTHOR), Debiec, Radoslaw M.1,5 (AUTHOR), Peloso, Gina M.1,2 (AUTHOR) gpeloso@bu.edu, Al-Kassou, Baravan6 (AUTHOR) baravan.al-kassou@ukbonn.de, Aranki, Sary7 (AUTHOR), Ashikhmina Swan, Elena8 (AUTHOR), Ballotta, Andrea9 (AUTHOR) andrea.ballotta@libero.it, Bellino, Michele10 (AUTHOR) michelebellino8@gmail.com, Björck, Hanna M.11,12 (AUTHOR) hanna.bjorck@ki.se, Boureau, Anne Sophie13 (AUTHOR), Braund, Peter S.5 (AUTHOR) psb7@leicester.ac.uk, Corriveau, François14 (AUTHOR) francois.dagenais@fmed.ulaval.ca, Dagenais, François1 (AUTHOR) francois.dagenais@fmed.ulaval.ca, Folkersen, Lasse15 (AUTHOR) lassefolkersen@gmail.com, Forte, Amalia16 (AUTHOR) forte.amalia@gmail.com, Francke, Michael D.7 (AUTHOR) Michael.d.francke@kp.org, Frigiola, Alessandro17 (AUTHOR) aledellacorte@libero.it
Source: Circulation. 4/7/2026, Vol. 153 Issue 14, p1060-1076. 17p.
Database: Academic Search Ultimate
Description
ISSN:00097322
DOI:10.1161/CIRCULATIONAHA.125.074752