Association between early methadone dose titration and treatment discontinuation and opioid toxicity: A retrospective cohort study.

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Title: Association between early methadone dose titration and treatment discontinuation and opioid toxicity: A retrospective cohort study.
Authors: Garg, Ria1,2 (AUTHOR) ria.garg@mail.utoronto.ca, Luo, Jin1 (AUTHOR), Bozinoff, Nikki3,4 (AUTHOR), Sproule, Beth2,5,6 (AUTHOR), Antoniou, Tony1 (AUTHOR), Wyman, Jennifer4,7 (AUTHOR), Leece, Pamela4,8,9 (AUTHOR), Munro, Charlotte10 (AUTHOR), Besharh, Jes10 (AUTHOR), Gomes, Tara1,2,11,12 (AUTHOR)
Source: PLoS Medicine. 4/9/2026, Vol. 23 Issue 4, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:15491277
DOI:10.1371/journal.pmed.1004748