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UBE2T‐Driven p53 Degradation Rewires Glycolysis to Orchestrate Lactylation‐Mediated CAFs Activation and ECM Deposition in Pancreatic Cancer.

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Title: UBE2T‐Driven p53 Degradation Rewires Glycolysis to Orchestrate Lactylation‐Mediated CAFs Activation and ECM Deposition in Pancreatic Cancer.
Authors: Ma, Yong1,2,3 (AUTHOR), Liu, Wenbo1,2,3 (AUTHOR), Li, Mingdou1,2,3 (AUTHOR), Wang, Tao1,2,3 (AUTHOR), Zhao, Bin1,2,3 (AUTHOR), Wang, Keshen4 (AUTHOR), He, Qichen1,2,3 (AUTHOR), Sun, Haonan1,2,3 (AUTHOR), Qing, Huiguo1,2 (AUTHOR), Guan, Xiaoying5 (AUTHOR), Shi, Wengui3,6 (AUTHOR), Qin, Long3,6 (AUTHOR), Dong, Yuman3,6 (AUTHOR), Zhou, Huinian2,3 (AUTHOR), Yu, Zeyuan2,3 (AUTHOR) yuzy17@lzu.edu.cn, Jiang, Xiangyan2,3 (AUTHOR) jiangxiangyan@lzu.edu.cn, Jiao, Zuoyi2,3 (AUTHOR) jiaozy@lzu.edu.cn
Source: Advanced Science. 4/17/2026, Vol. 13 Issue 22, p1-15. 15p.
Database: Academic Search Ultimate
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Description
ISSN:21983844
DOI:10.1002/advs.202514933