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First‐In‐Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT‐02 Freebase, a CNS‐Penetrant NLRP3 Inhibitor.

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Title: First‐In‐Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT‐02 Freebase, a CNS‐Penetrant NLRP3 Inhibitor.
Authors: Smidt, Lisanne C. A.1,2 (AUTHOR), Moerland, Matthijs1,2 (AUTHOR), Jansen, Manon A. A.1,2 (AUTHOR), Kremer, Philip H. C.1,2 (AUTHOR), Sille, Alexandra A. J.1,2 (AUTHOR), Strugala, Pamela K.1 (AUTHOR), Klaassen, Erica S.1 (AUTHOR), Auger, Anick3 (AUTHOR), Jananji, Silvana3 (AUTHOR), Faidi, Rania3 (AUTHOR), Pike, Kelly A.3 (AUTHOR), Warner, Loraine4 (AUTHOR), Matta, Andre4 (AUTHOR), Valencia, Xavier4 (AUTHOR), Spiegelstein, Ofer4 (AUTHOR) ospiegelstein@gmail.com
Source: CTS: Clinical & Translational Science. May2026, Vol. 19 Issue 5, p1-11. 11p.
Database: Academic Search Ultimate
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  Data: <searchLink fieldCode="JN" term="%22CTS%3A+Clinical+%26+Translational+Science%22">CTS: Clinical & Translational Science</searchLink>. May2026, Vol. 19 Issue 5, p1-11. 11p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=193814519
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              Text: May2026
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