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Structural basis for sarbecovirus Rc-o319 spike adaptation to Rhinolophus cornutus Bat ACE2 and constraints on switching to human ACE2.

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Title: Structural basis for sarbecovirus Rc-o319 spike adaptation to Rhinolophus cornutus Bat ACE2 and constraints on switching to human ACE2.
Authors: Wang, Jingjing1,2 (AUTHOR), Li, Zexuan1,3 (AUTHOR), Ma, Yong1,2 (AUTHOR), Li, Zimu1,2,4,5 (AUTHOR), Yuan, Hang1,2,3 (AUTHOR), Niu, Chuanying1,5 (AUTHOR), Teng, Yifeng1,3 (AUTHOR), Liu, Banghui1,2 (AUTHOR), Li, Mei4 (AUTHOR), Zhou, Min4 (AUTHOR), Liu, Wenxiu4 (AUTHOR), Feng, Huimin1 (AUTHOR), Chen, Jing4 (AUTHOR), He, Jun1,2 (AUTHOR), Chen, Xinwen4,6 (AUTHOR) chen_xinwen@gzlab.ac.cn, Xiong, Xiaoli1,2,4 (AUTHOR) xiong_xiaoli@gzlab.ac.cn
Source: PLoS Pathogens. 5/21/2026, Vol. 22 Issue 5, p1-28. 28p.
Database: Academic Search Ultimate
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ISSN:15537366
DOI:10.1371/journal.ppat.1014245