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Aberrant intra‐epithelial lymphocytes cause enterocyte cell death in refractory celiac disease by CD103‐β7‐receptor‐mediated granzyme‐B degranulation which can be restored by etrolizumab.

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Title: Aberrant intra‐epithelial lymphocytes cause enterocyte cell death in refractory celiac disease by CD103‐β7‐receptor‐mediated granzyme‐B degranulation which can be restored by etrolizumab.
Authors: Castelijn, Daan A R1,2,3 (AUTHOR), van de Water, Jolanda M W1 (AUTHOR), de Baaij, Laura R1 (AUTHOR), McGlinchy, Bridget S1 (AUTHOR), van Leeuwen, Michelle1 (AUTHOR), Joosten, Sander P J2 (AUTHOR), Alberts, Nikita2 (AUTHOR), Rossi, Margherita2 (AUTHOR), Reijm, Martine4 (AUTHOR), Hollander, Jolien C4 (AUTHOR), Bonnet, Petra4 (AUTHOR), Kooy‐Winkelaar, Yvonne M C5 (AUTHOR), Koning, Frits5 (AUTHOR), Pals, Steven T2 (AUTHOR), Bouma, Gerd1 (AUTHOR), Meijer, Chris J L M2 (AUTHOR), Bontkes, Hetty J4 (AUTHOR), Mulder, Chris J J1 (AUTHOR), Cillessen, Saskia A G M2 (AUTHOR) sagm.cillessen@amsterdamumc.nl
Source: Clinical & Translational Immunology. May2026, Vol. 15 Issue 5, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:20500068
DOI:10.1002/cti2.70099