HIV-1 BG505 SOSIP immunization induced B cell expansion targeting the 465-glycan hole, with neutralizing antibodies exhibiting distinct binding modes and mechanisms of virus inhibition.

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Title: HIV-1 BG505 SOSIP immunization induced B cell expansion targeting the 465-glycan hole, with neutralizing antibodies exhibiting distinct binding modes and mechanisms of virus inhibition.
Authors: Myers, August1 (AUTHOR), Chandravanshi, Monika2,3 (AUTHOR), Whitmore, Leanne S.1,4 (AUTHOR), Kohrn, Brendan F.1 (AUTHOR), Negash, Amina1 (AUTHOR), Nguyen, Dung N.2,3 (AUTHOR), Ralli-Jain, Pooja1 (AUTHOR), Cruickshank, Kendra1 (AUTHOR), Upadhyay, Amit A.5,6 (AUTHOR), Charles, Tysheena6,7 (AUTHOR), Edwards, Christopher T.5,6 (AUTHOR), Hunter, Eric5,6 (AUTHOR), Amara, Rama R.6,7 (AUTHOR), Korzeniowski, Marek K.2,3 (AUTHOR), Niu, Ling2,3 (AUTHOR), Pozharski, Edwin8,9 (AUTHOR), Tolbert, William D.2,3 (AUTHOR), Bosinger, Steven E.5,6 (AUTHOR), Kennedy, Scott R.1 (AUTHOR), Pazgier, Marzena2 (AUTHOR) marzena.pazgier@usuhs.edu
Source: PLoS Pathogens. 6/5/2026, Vol. 22 Issue 6, p1-28. 28p.
Database: Academic Search Ultimate
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ISSN:15537366
DOI:10.1371/journal.ppat.1014268