Species, cell proliferation state and oxygen partial pressure are major factors in the in vitro toxicity of repurposed potential ADPKD drugs in human and murine renal proximal tubule cells.

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Title: Species, cell proliferation state and oxygen partial pressure are major factors in the in vitro toxicity of repurposed potential ADPKD drugs in human and murine renal proximal tubule cells.
Authors: Sotiropoulou, Paraskevi1 (AUTHOR) Paraskevi.Sotiropoulou@uni-konstanz.de, Gerdemann, Andrea2 (AUTHOR), Jovanovic, Stefan3 (AUTHOR), Humpf, Hans-Ulrich2 (AUTHOR), Bürkle, Alexander3 (AUTHOR), Dietrich, Daniel R.1 (AUTHOR) Daniel.Dietrich@uni-konstanz.de
Source: Archives of Toxicology. Jun2026, p1-21. 21p.
Database: Academic Search Ultimate
Description
ISSN:03405761
DOI:10.1007/s00204-026-04472-2