Species, cell proliferation state and oxygen partial pressure are major factors in the in vitro toxicity of repurposed potential ADPKD drugs in human and murine renal proximal tubule cells.

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Title: Species, cell proliferation state and oxygen partial pressure are major factors in the in vitro toxicity of repurposed potential ADPKD drugs in human and murine renal proximal tubule cells.
Authors: Sotiropoulou, Paraskevi1 (AUTHOR) Paraskevi.Sotiropoulou@uni-konstanz.de, Gerdemann, Andrea2 (AUTHOR), Jovanovic, Stefan3 (AUTHOR), Humpf, Hans-Ulrich2 (AUTHOR), Bürkle, Alexander3 (AUTHOR), Dietrich, Daniel R.1 (AUTHOR) Daniel.Dietrich@uni-konstanz.de
Source: Archives of Toxicology. Jun2026, p1-21. 21p.
Database: Academic Search Ultimate
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  Data: Species, cell proliferation state and oxygen partial pressure are major factors in the in vitro toxicity of repurposed potential ADPKD drugs in human and murine renal proximal tubule cells.
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  Data: <searchLink fieldCode="JN" term="%22Archives+of+Toxicology%22">Archives of Toxicology</searchLink>. Jun2026, p1-21. 21p.
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      – Type: doi
        Value: 10.1007/s00204-026-04472-2
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      – Code: eng
        Text: English
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        PageCount: 21
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      – TitleFull: Species, cell proliferation state and oxygen partial pressure are major factors in the in vitro toxicity of repurposed potential ADPKD drugs in human and murine renal proximal tubule cells.
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            NameFull: Sotiropoulou, Paraskevi
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            NameFull: Gerdemann, Andrea
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            NameFull: Jovanovic, Stefan
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            NameFull: Humpf, Hans-Ulrich
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            NameFull: Bürkle, Alexander
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            – D: 27
              M: 06
              Text: Jun2026
              Type: published
              Y: 2026
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