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Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation

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Bibliographic Details
Title: Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation
Authors: Tegley, Christopher M.1 ctegley@amgen.com, Viswanadhan, Vellarkad N.1, Biswas, Kaustav1, Frohn, Michael J.1, Peterkin, Tanya A.N.1, Chang, Catherine1, Bürli, Roland W.1, Dao, Jennifer H.1, Veith, Henrike2, Rogers, Norma2, Yoder, Sean C.2, Biddlecome, Gloria2, Tagari, Philip1, Allen, Jennifer R.1, Hungate, Randall W.1
Source: Bioorganic & Medicinal Chemistry Letters. Jul2008, Vol. 18 Issue 14, p3925-3928. 4p.
Database: Academic Search Ultimate
Description
ISSN:0960894X
DOI:10.1016/j.bmcl.2008.06.031