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The discovery and optimisation of pyrido[2,3-d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase

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Bibliographic Details
Title:	The discovery and optimisation of pyrido[2,3-d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase
Authors:	Malagu, Karine¹, Duggan, Heather¹, Menear, Keith¹, Hummersone, Marc¹, Gomez, Sylvie¹, Bailey, Christine¹, Edwards, Peter¹, Drzewiecki, Jan¹, Leroux, Frédéric¹, Quesada, Mar Jimenez¹, Hermann, Gesine¹, Maine, Stephanie¹, Molyneaux, Carrie-Anne¹, Le Gall, Armelle¹, Pullen, James¹, Hickson, Ian¹, Smith, Lisa¹, Maguire, Sharon¹, Martin, Niall¹, Smith, Graeme^1,2
Source:	Bioorganic & Medicinal Chemistry Letters. Oct2009, Vol. 19 Issue 20, p5950-5953. 4p.
Database:	Academic Search Ultimate

Description
ISSN:	0960894X
DOI:	10.1016/j.bmcl.2009.08.038