Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: The discovery of AZD8055 and AZD2014
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| Title: | Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: The discovery of AZD8055 and AZD2014 |
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| Authors: | Pike, Kurt G.1 kurt.pike@astrazeneca.com, Malagu, Karine2, Hummersone, Marc G.2, Menear, Keith A.2, Duggan, Heather M.E.2, Gomez, Sylvie2, Martin, Niall M.B.2, Ruston, Linette1, Pass, Sarah L.1, Pass, Martin1 |
| Source: | Bioorganic & Medicinal Chemistry Letters. Mar2013, Vol. 23 Issue 5, p1212-1216. 5p. |
| Database: | Academic Search Ultimate |
| ISSN: | 0960894X |
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| DOI: | 10.1016/j.bmcl.2013.01.019 |