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Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

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Title: Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans
Authors: Julien, Jean-Philippe1,2,3, Sok, Devin2,3,4, Khayat, Reza1,2,3, Lee, Jeong Hyun1,2,3, Doores, Katie J.2,3,4, Walker, Laura M.2,3,4, Ramos, Alejandra2, Diwanji, Devan C.1,2,3, Pejchal, Robert1,2,3, Cupo, Albert5, Katpally, Umesh5, Depetris, Rafael S.5, Stanfield, Robyn L.1,2,3, McBride, Ryan6, Marozsan, Andre J.5, Paulson, James C.1,6, Sanders, Rogier W.5,7, Moore, John P.5, Burton, Dennis R.2,3,4,8, Poignard, Pascal2,4
Source: PLoS Pathogens. May2013, Vol. 9 Issue 5, p1-15. 15p. 4 Diagrams, 2 Charts, 1 Graph.
Database: Academic Search Ultimate
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ISSN:15537366
DOI:10.1371/journal.ppat.1003342