Structural optimization of cyclic sulfonamide based novel HIV-1 protease inhibitors to picomolar affinities guided by X-ray crystallographic analysis.

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Bibliographic Details
Title: Structural optimization of cyclic sulfonamide based novel HIV-1 protease inhibitors to picomolar affinities guided by X-ray crystallographic analysis.
Authors: Ganguly, Ashit K.1 akganguly1@aol.com, Alluri, Sesha S.1, Wang, Chih-Hung1, Antropow, Alyssa1, White, Alex1, Caroccia, Danielle1, Biswas, Dipshikha1, Kang, Eunhee1, Zhang, Li-Kang2, Carroll, Steven S.3, Burlein, Christine3, Fay, John3, Orth, Peter4, Strickland, Corey4
Source: Tetrahedron. May2014, Vol. 70 Issue 18, p2894-2904. 11p.
Database: Academic Search Ultimate
Description
ISSN:00404020
DOI:10.1016/j.tet.2014.03.038