Identification of (R)-6-(1-(4-Cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic Acid, a HighlyPotent and Selective Nonsteroidal Mineralocorticoid Receptor Antagonist.

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Title: Identification of (R)-6-(1-(4-Cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic Acid, a HighlyPotent and Selective Nonsteroidal Mineralocorticoid Receptor Antagonist.
Authors: Casimiro-Garcia, Agustin1, Piotrowski, David W.1, Ambler, Catherine1, Arhancet, Graciela B.1, Banker, Mary Ellen1, Banks, Tereece1, Boustany-Kari, Carine M.1, Cai, Cuiman1, Chen, Xiangyang1, Eudy, Rena1, Hepworth, David1, Hulford, Catherine A.1, Jennings, Sandra M.1, Loria, Paula M.1, Meyers, Marvin J.1, Petersen, Donna N.1, Raheja, Neil K.1, Sammons, Matthew1, She, Li1, Song, Kun1
Source: Journal of Medicinal Chemistry. May2014, Vol. 57 Issue 10, p4273-4288. 16p.
Database: Academic Search Ultimate
Description
ISSN:00222623
DOI:10.1021/jm500206r