Metabolic reconstruction and validation: characterisation of two aromatic amino acid hydroxylases from Toxoplasma gondii
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| Title: | Metabolic reconstruction and validation: characterisation of two aromatic amino acid hydroxylases from Toxoplasma gondii |
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| Authors: | Gaskell, Elizabeth Anne |
| Summary: | The Apicomplexa are a phylum of single celled parasitic organisms that cause a wide range of diseases from human malaria and encephalitis in AlDs patients to coccidiosis in chickens and East Coast fever in cattle. There has been a huge effort in recent years to sequence the genomes of many of these pathogens. This thesis begins by taking a comparative genomics approach to predict novel metabolic pathways from the newly sequenced genomes of Toxoplasma gondii and Eimeha tenella. |
| URL: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493552 |
| Database: | OpenDissertations |
| Abstract: | The Apicomplexa are a phylum of single celled parasitic organisms that cause a wide range of diseases from human malaria and encephalitis in AlDs patients to coccidiosis in chickens and East Coast fever in cattle. There has been a huge effort in recent years to sequence the genomes of many of these pathogens. This thesis begins by taking a comparative genomics approach to predict novel metabolic pathways from the newly sequenced genomes of Toxoplasma gondii and Eimeha tenella. |
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