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The effect of antidepressant treatment on brain-derived neurotropic factor expression in the rat hippocampus

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Title: The effect of antidepressant treatment on brain-derived neurotropic factor expression in the rat hippocampus
Authors: Khundakar, Ahmad Adam
Summary: Enhanced BDNF expression has been implicated in the mechanisms of action of antidepressant treatment. Previous findings have shown that chronic antidepressant drug treatment produces a ’bi-phasic effect’ on total BDNF gene expression, i.e. down-regulation at 4h and up-regulation at 24h. The earlier effect is common to acute administration, while the latter is unique to chronic treatment.
URL: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.649953
Database: OpenDissertations
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An: ddu.oai.ethos.bl.uk.649953
AccessLevel: 6
PubType: Dissertation/ Thesis
PubTypeId: dissertation
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  Data: The effect of antidepressant treatment on brain-derived neurotropic factor expression in the rat hippocampus
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  Data: Enhanced BDNF expression has been implicated in the mechanisms of action of antidepressant treatment. Previous findings have shown that chronic antidepressant drug treatment produces a ’bi-phasic effect’ on total BDNF gene expression, i.e. down-regulation at 4h and up-regulation at 24h. The earlier effect is common to acute administration, while the latter is unique to chronic treatment.
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RecordInfo BibRecord:
  BibEntity:
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: 616.85
        Type: general
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      – TitleFull: The effect of antidepressant treatment on brain-derived neurotropic factor expression in the rat hippocampus
        Type: main
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          Name:
            NameFull: Khundakar, Ahmad Adam
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      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2004
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