Bibliographic Details
| Title: |
anti Ethyl β-thienyl-β-amino-α-hydroxy propionate: a regio and stereoselective ring opening of trans ethyl 2-thienyl-glycidate |
| Authors: |
Solladié-Cavallo, A.1 cavallo@chimie.u-strasbg.fr, Lupattelli, P.1,2, Bonini, C.2, De Bonis, M.1,2 |
| Source: |
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2003, Vol. 44 Issue 27, p5075. 4p. |
| Subjects: |
Epoxy compounds, Aldehydes |
| Abstract: |
anti Ethyl β-thienyl-β-amino-α-hydroxy propionate was obtained regio- and diastereo-selectively in three steps and 45% overall yield, while 95% syn ethyl β-chloro-β-thienyl-α-hydroxy ester was obtained regio-selectively in two steps and 50% overall yield, both from 2-thienyl aldehyde. [Copyright &y& Elsevier] |
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| Database: |
Engineering Source |
