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US-guided transcutaneous tru-cut biopsy of laryngo-hypopharyngeal lesions.

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Title:	US-guided transcutaneous tru-cut biopsy of laryngo-hypopharyngeal lesions.
Authors:	Preda L (AUTHOR), De Fiori E (AUTHOR), Rampinelli C (AUTHOR), Ansarin M (AUTHOR), Petralia G (AUTHOR), Maffini F (AUTHOR), Alterio D (AUTHOR), Bonello L (AUTHOR), Chiesa F (AUTHOR), Bellomi M (AUTHOR), Preda, Lorenzo¹ (AUTHOR), De Fiori, Elvio (AUTHOR), Rampinelli, Cristiano (AUTHOR), Ansarin, Mohssen (AUTHOR), Petralia, Giuseppe (AUTHOR), Maffini, Fausto (AUTHOR), Alterio, Daniela (AUTHOR), Bonello, Luke (AUTHOR), Chiesa, Fausto (AUTHOR), Bellomi, Massimo (AUTHOR)
Source:	European Radiology. Jun2010, Vol. 20 Issue 6, p1450-1455. 6p.
Abstract:	Objective: To evaluate the feasibility and performance of ultrasound-guided transcutaneous tru-cut biopsy (USGTCB) in selected patients (with stenosis of airways or difficult intubation or contraindication to general anaesthesia) with untreated or previously treated suspicious laryngo-hypopharyngeal masses.Methods: Biopsies were performed with a free-hand technique by a single radiologist. Thirty-six USGTCBs were scheduled in 34 patients (24 males, 10 females; age range 47-95 years). Two USGTCBs were not performed, as lesions were not detectable: therefore, 16 USGTCBs were performed for an untreated mass suspicious for malignancy and 18 were performed for a mass suspicious for recurrence after radiotherapy alone, or associated with endoscopic laser surgery or chemotherapy.Results: USGTCB diagnosed 25 squamous cell carcinomas (73.5%) and nine benign lesions (26.5%); no false positives and two false negatives were reported, both in patients previously treated with radiotherapy. The sensitivity, specificity, positive and negative predictive value of the technique was 92.5%, 100%, 100% and 77.7% respectively, with no major complications.Conclusion: Although biopsy under microlaryngoscopy remains the "gold-standard" technique, USGTCB is feasible, carries the advantages of avoiding general anaesthesia, is suitable for outpatients and is cost-effective. If applied to selected patients, it could be considered for the histological diagnosis of both primary and recurrent laryngo-hypopharyngeal masses. [ABSTRACT FROM AUTHOR]
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Database:	Engineering Source
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