Bibliographic Details
| Title: |
Chiral Primary Amine Catalyzed Asymmetric Tandem Reduction-Michael Addition-Protonation Reaction between Alkylidene Meldrum's Acid and α-Substituted Vinyl Ketones. |
| Authors: |
Marquer, Nicolas Le1, Laurent, Mathieu Yves1, Martel, Arnaud1 arnaud.martel@univ-lemans.fr |
| Source: |
Synthesis. 2015, Vol. 47 Issue 15, p2207-2216. 10p. |
| Subjects: |
Cost effectiveness, Octane, Semicarbazones, Solid-phase synthesis, Microwaves |
| Abstract: |
One-pot three-component tandem reduction-Michael addition-protonation reactions of alkylidene Meldrum's acids to α-substituted vinyl ketones have been developed by using a chiral primary amine as the organocatalyst, affording the products in excellent yields and with good enantioselectivity. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
