Chiral Primary Amine Catalyzed Asymmetric Tandem Reduction-Michael Addition-Protonation Reaction between Alkylidene Meldrum's Acid and α-Substituted Vinyl Ketones.

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Title: Chiral Primary Amine Catalyzed Asymmetric Tandem Reduction-Michael Addition-Protonation Reaction between Alkylidene Meldrum's Acid and α-Substituted Vinyl Ketones.
Authors: Marquer, Nicolas Le1, Laurent, Mathieu Yves1, Martel, Arnaud1 arnaud.martel@univ-lemans.fr
Source: Synthesis. 2015, Vol. 47 Issue 15, p2207-2216. 10p.
Subjects: Cost effectiveness, Octane, Semicarbazones, Solid-phase synthesis, Microwaves
Abstract: One-pot three-component tandem reduction-Michael addition-protonation reactions of alkylidene Meldrum's acids to α-substituted vinyl ketones have been developed by using a chiral primary amine as the organocatalyst, affording the products in excellent yields and with good enantioselectivity. [ABSTRACT FROM AUTHOR]
Copyright of Synthesis is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 108512567
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  Data: Chiral Primary Amine Catalyzed Asymmetric Tandem Reduction-Michael Addition-Protonation Reaction between Alkylidene Meldrum's Acid and α-Substituted Vinyl Ketones.
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  Data: <searchLink fieldCode="AR" term="%22Marquer%2C+Nicolas+Le%22">Marquer, Nicolas Le</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Laurent%2C+Mathieu+Yves%22">Laurent, Mathieu Yves</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Martel%2C+Arnaud%22">Martel, Arnaud</searchLink><relatesTo>1</relatesTo><i> arnaud.martel@univ-lemans.fr</i>
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  Data: <searchLink fieldCode="JN" term="%22Synthesis%22">Synthesis</searchLink>. 2015, Vol. 47 Issue 15, p2207-2216. 10p.
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  Data: <searchLink fieldCode="DE" term="%22Cost+effectiveness%22">Cost effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Octane%22">Octane</searchLink><br /><searchLink fieldCode="DE" term="%22Semicarbazones%22">Semicarbazones</searchLink><br /><searchLink fieldCode="DE" term="%22Solid-phase+synthesis%22">Solid-phase synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Microwaves%22">Microwaves</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: One-pot three-component tandem reduction-Michael addition-protonation reactions of alkylidene Meldrum's acids to α-substituted vinyl ketones have been developed by using a chiral primary amine as the organocatalyst, affording the products in excellent yields and with good enantioselectivity. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Synthesis is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1055/s-0034-1380717
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      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 2207
    Subjects:
      – SubjectFull: Cost effectiveness
        Type: general
      – SubjectFull: Octane
        Type: general
      – SubjectFull: Semicarbazones
        Type: general
      – SubjectFull: Solid-phase synthesis
        Type: general
      – SubjectFull: Microwaves
        Type: general
    Titles:
      – TitleFull: Chiral Primary Amine Catalyzed Asymmetric Tandem Reduction-Michael Addition-Protonation Reaction between Alkylidene Meldrum's Acid and α-Substituted Vinyl Ketones.
        Type: main
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            NameFull: Marquer, Nicolas Le
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            NameFull: Laurent, Mathieu Yves
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            NameFull: Martel, Arnaud
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            – D: 01
              M: 08
              Text: 2015
              Type: published
              Y: 2015
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              Value: 47
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              Value: 15
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            – TitleFull: Synthesis
              Type: main
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