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Measurements of fundamental properties of homogeneous tissue phantoms.

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Title: Measurements of fundamental properties of homogeneous tissue phantoms.
Authors: Wróbel, Maciej S.1 maciejswrobel@gmail.com, Popov, Alexey P.2, Bykov, Alexander V.2, Kinnunen, Matti2, Jędrzejewska-Szczerska, Malgorzata1, Tuchin, Valery V.2,3,4
Source: Journal of Biomedical Optics. Apr2015, Vol. 20 Issue 4, p1-10. 10p.
Subjects: Tissues -- Models, Imaging phantoms, Optical coherence tomography, Body composition models, Absorbed dose
Abstract: We present the optical measurement techniques used in human skin phantom studies. Their accuracy and the sources of errors in microscopic parameters' estimation of the produced phantoms are described. We have produced optical phantoms for the purpose of simulating human skin tissue at the wavelength of 930 nm. Optical coherence tomography was used to measure the thickness and surface roughness and to detect the internal in homogeneities. A more detailed study of phantom surface roughness was carried out with the optical profilometer. Reflectance, transmittance, and collimated transmittance of phantoms were measured using an integrating-sphere spectrometer setup. The scattering and absorption coefficients were calculated with the inverse adding-doubling method. The reduced scattering coefficient at 930 nm was found to be 1.57 ±0.14 mm-1 and the absorption was 0.22 ± 0.03 mm-1. The retrieved optical properties of phantoms are in agree- ment with the data found in the literature for real human tissues. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
Description
Abstract:We present the optical measurement techniques used in human skin phantom studies. Their accuracy and the sources of errors in microscopic parameters' estimation of the produced phantoms are described. We have produced optical phantoms for the purpose of simulating human skin tissue at the wavelength of 930 nm. Optical coherence tomography was used to measure the thickness and surface roughness and to detect the internal in homogeneities. A more detailed study of phantom surface roughness was carried out with the optical profilometer. Reflectance, transmittance, and collimated transmittance of phantoms were measured using an integrating-sphere spectrometer setup. The scattering and absorption coefficients were calculated with the inverse adding-doubling method. The reduced scattering coefficient at 930 nm was found to be 1.57 ±0.14 mm-1 and the absorption was 0.22 ± 0.03 mm-1. The retrieved optical properties of phantoms are in agree- ment with the data found in the literature for real human tissues. [ABSTRACT FROM AUTHOR]
ISSN:10833668
DOI:10.1117/1.JBO.20.4.045004