Bibliographic Details
| Title: |
Proteobacteria: microbial signature of dysbiosis in gut microbiota. |
| Authors: |
Shin, Na-Ri1, Whon, Tae Woong1, Bae, Jin-Woo1 baejw@khu.ac.kr |
| Source: |
Trends in Biotechnology. Sep2015, Vol. 33 Issue 9, p496-503. 8p. |
| Subjects: |
Inflammation, Proteobacteria, Gut microbiota, Hosts (Biology), Disease risk factors, Disease prevalence |
| Abstract: |
Recent advances in sequencing techniques, applied to the study of microbial communities, have provided compelling evidence that the mammalian intestinal tract harbors a complex microbial community whose composition is a critical determinant of host health in the context of metabolism and inflammation. Given that an imbalanced gut microbiota often arises from a sustained increase in abundance of the phylum Proteobacteria , the natural human gut flora normally contains only a minor proportion of this phylum. Here, we review studies that explored the association between an abnormal expansion of Proteobacteria and a compromised ability to maintain a balanced gut microbial community. We also propose that an increased prevalence of Proteobacteria is a potential diagnostic signature of dysbiosis and risk of disease. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
