Free-Breathing, Motion-Corrected, Highly Efficient Whole Heart T2 Mapping at 3T with Hybrid Radial-Cartesian Trajectory.
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| Title: | Free-Breathing, Motion-Corrected, Highly Efficient Whole Heart T |
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| Authors: | Yang, Hsin‐Jung1,2, Sharif, Behzad1, Pang, Jianing1, Kali, Avinash1,2, Bi, Xiaoming3, Cokic, Ivan1, Li, Debiao1,2,4, Dharmakumar, Rohan1,4,5 |
| Source: | Magnetic Resonance in Medicine. Jan2016, Vol. 75 Issue 1, p126-136. 11p. |
| Abstract: | Purpose: To develop and test a time-efficient, free-breathing, whole heart T2 mapping technique at 3.0T. Methods: ECG-triggered three-dimensional (3D) images were acquired with different T2 preparations at 3.0T during free breathing. Respiratory motion was corrected with a navigatorguided motion correction framework at near perfect efficiency. Image intensities were fit to a monoexponential function to derive myocardial T2 maps. The proposed 3D, free breathing, motion-corrected (3D-FB-MoCo) approach was studied in ex vivo canine hearts and kidneys, healthy volunteers, and canine subjects with acute myocardial infarction (AMI). Results: Ex vivo T2 values from proposed 3D T2-prep gradient echo were not different from two-dimensional (2D) spin echo (P=0.7) and T2-prep balanced steady-state free precession (bSSFP) (P=0.7). In healthy volunteers, compared with 3DFB- MoCo and breath-held 2D T2-prep bSSFP (2D-BH), non- motion-corrected (3D-FB-Non-MoCo) myocardial T2 was longer, had a larger coefficient of variation (COV), and had a lower image quality (IQ) score (T2=40.3 ms, COV=38%, and IQ=2.3; all P<0.05). Conversely, the mean and COV and IQ of 3D-FB-MoCo (T2=37.7 ms, COV=17%, and IQ=3.5) and 2D-BH (T2=38.0 ms, COV=15%, and IQ=3.8) were not different (P=0.99, P=0.74, and P=0.14, respectively). In AMI, T2 values and edema volumes from 3D-FB-MoCo and 2D-BH were closely correlated (R2=0.88 and 0.96, respectively). Conclusion: The proposed whole heart T2 mapping approach can be performed within 5 min with similar accuracy to that of the 2D-BH T2 mapping approach. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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