Bibliographic Details
| Title: |
Synthesis of a New Stable Conformationally Constrained 2,7-Anhydrosialic Acid Derivative. |
| Authors: |
Ke-Gang Liu1, Hai-Bin Zhou, Bruno1, Yu-Lin Wu1, Zhu-Jun Yao1 yaoz@mail.sioc.ac.cn |
| Source: |
Journal of Organic Chemistry. 11/28/2003, Vol. 68 Issue 24, p9528-9531. 4p. 4 Diagrams. |
| Subjects: |
Sialic acids, Grignard reagents, Organic synthesis |
| Abstract: |
A stereoseletive synthesis of 2,7-anhydrosialic acid derivative 18 was achieved from D-glucono-δ-1actone. A highly syn-selective addition of Grignard reagent to the N-benzylimine 8 served as a key step. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
