High-Performance Liquid Chromatography-Diodic Array Detector, Fungistatic, and Anti-Morphogenical Analysis of Extracts from Psidium brownianum Mart. ex DC. Against Yeasts of the Genus Candida.

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Title: High-Performance Liquid Chromatography-Diodic Array Detector, Fungistatic, and Anti-Morphogenical Analysis of Extracts from Psidium brownianum Mart. ex DC. Against Yeasts of the Genus Candida.
Authors: Morais-Braga, Maria Flaviana B.1 (AUTHOR) flavianamoraisb@yahoo.como.br, Carneiro, Joara N. P.1 (AUTHOR), Machado, Antonio J. T.1 (AUTHOR), Sales, Débora L.1 (AUTHOR), Brito, Dara I.V.2 (AUTHOR), Albuquerque, Rosimeire S.1 (AUTHOR), Boligon, Aline A.3 (AUTHOR), Athayde, Margareth L.3 (AUTHOR), Calixto Júnior, João T.4 (AUTHOR), Souza, Djair S. L.5 (AUTHOR), Lima, Edeltrudes O.6 (AUTHOR), Menezes, Irwin R. A.2 (AUTHOR), Costa, José G. M.2 (AUTHOR), Ferreira, Felipe S.2 (AUTHOR), Coutinho, Henrique D. M.2 (AUTHOR)
Source: International Journal of Food Properties. 2016, Vol. 19 Issue 8, p1837-1851. 15p.
Subjects: High performance liquid chromatography, Infrared array detectors, Fungistats, Morphogenesis, Psidium
Abstract: We assessed extracts fromPsidium brownianumfor antifungal activity and identified the phenolic phytocompounds. Minimum inhibitory concentration was determined by microdilution and IC50was calculated. The minimun fungicidal concentration and the morphology ofCandidawere evaluated. Extracts analyzed by high-performance liquid chromatography demonstrated flavonoids and phenolic acids. The minimum inhibitory concentration was 8192 µg/mL and the IC50varied between 1056 and 5128 µg/mL. Extracts showed fungistatic effect and altered the dimorphism of the strains, being the better result observed using the decoction, that affected the fungal dimorphism of the strain CA ATCC40006 at 4096 µg/mL. [ABSTRACT FROM AUTHOR]
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Abstract:We assessed extracts fromPsidium brownianumfor antifungal activity and identified the phenolic phytocompounds. Minimum inhibitory concentration was determined by microdilution and IC50was calculated. The minimun fungicidal concentration and the morphology ofCandidawere evaluated. Extracts analyzed by high-performance liquid chromatography demonstrated flavonoids and phenolic acids. The minimum inhibitory concentration was 8192 µg/mL and the IC50varied between 1056 and 5128 µg/mL. Extracts showed fungistatic effect and altered the dimorphism of the strains, being the better result observed using the decoction, that affected the fungal dimorphism of the strain CA ATCC40006 at 4096 µg/mL. [ABSTRACT FROM AUTHOR]
ISSN:10942912
DOI:10.1080/10942912.2015.1079786