Bibliographic Details
| Title: |
The KA2 coupling reaction under green, solventless, heterogeneous catalysis. |
| Authors: |
Bosica, Giovanna1 giovanna.bosica@um.edu.mt, Abdilla, Roderick1 |
| Source: |
Journal of Molecular Catalysis A: Chemistry. Jan2017 Part B, Vol. 426, p542-549. 8p. |
| Subjects: |
Coupling reactions (Chemistry), Heterogeneous catalysis, Secondary amines, Catalysts recycling, Chemical reactions |
| Abstract: |
Amberlyst A-21 supported CuI was found to be highly efficient novel heterogeneous catalyst for the three-component reaction between ketones, amines and alkynes, commonly called KA 2 -coupling. This inexpensive, easy-to-prepare, simple and recyclable catalyst has been employed in solventless conditions in the KA 2 coupling reaction involving both primary and secondary amines, ketones and various alkynes. The secondary and tertiary propargylamine products were obtained in good to excellent results in moderate reaction times. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
