Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis.

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Title: Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis.
Authors: Mangeolle, Tristan1,2 t.mangeolle@nancy.unicancer.fr, Yakavets, Ilya1,2,3 i.yakavets@nancy.unicancer.fr, Marchal, Sophie1,2 s.marchal@nancy.unicancer.fr, Debayle, Manon4 manon.debayle@espci.fr, Pons, Thomas4 thomas.pons@espci.fr, Bezdetnaya, Lina1,2 l.bolotine@nancy.unicancer.fr, Marchal, Frédéric1,5 f.marchal@nancy.unicancer.fr
Source: Nanomaterials (2079-4991). Aug2018, Vol. 8 Issue 8, p572. 20p.
Subjects: Nanoparticles, Ovarian cancer treatment, Cytoreductive surgery
Abstract: Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed nearand short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
Description
Abstract:Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed nearand short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application. [ABSTRACT FROM AUTHOR]
ISSN:20794991
DOI:10.3390/nano8080572