View in EDS

Enhancing the sensitivity of point-of-use electrochemical microfluidic sensors by ion concentration polarisation – A case study on arsenic.

Saved in:
Bibliographic Details
Title: Enhancing the sensitivity of point-of-use electrochemical microfluidic sensors by ion concentration polarisation – A case study on arsenic.
Authors: Subramanian, Vidhya1,2 (AUTHOR), Lee, Sangjun3 (AUTHOR), Jena, Sanjoy4 (AUTHOR), Jana, Sourav Kanti1 (AUTHOR), Ray, Debdutta4 (AUTHOR), Kim, Sung Jae3,5,6 (AUTHOR), Thalappil, Pradeep1 (AUTHOR) pradeep@iitm.ac.in
Source: Sensors & Actuators B: Chemical. Feb2020, Vol. 304, pN.PAG-N.PAG. 1p.
Subjects: Electrochemical sensors, Microfluidic devices, Water quality monitoring, Fluidics, Labs on a chip, Arsenic, Metal detectors, Arsenic compounds
Geographic Terms: India
Abstract: • First report of utilising Ion Concentration Polarisation for concentrating ions in a microfluidic device. • Facile fabrication technique for the development of multiple layer Lab on a Chip device without the use of valves. • Detection of As3+ to 1 ppb without surface modification of the working electrode. • Detection of 7 ppb of As3+ in field sample without any pre-treatment of the sample. Point of use (POU) sensors are extremely relevant, being capable of providing fast and reliable analysis in remote and resource-limited settings. Of all the diverse techniques utilised for POU sensors, a combination of electrochemistry and microfluidics may have the greatest potential towards quantitative assessment of heavy metal ions. The major challenge in combining these for sensing applications lies in the complexity of fabricating integrated devices and the insufficient quantity of analytes in the sample volume. To address these issues, we have developed a radial microfluidic device capable of electrokinetic preconcentration by ion concentration polarization (ICP) and integrated it with electroactive surfaces. The proposed sensor is the first demonstration of concentration of heavy metal ions by ICP and its quantitative assessment by voltammetry. Utilising the integrated sensor, we have shown the sensing of As3+ down to 1 ppb by linear sweep voltammetry with ∼40 μL of sample. The sensor was also tested successfully for sensing As3+ in a field sample from an arsenic affected region of India. The sensor was also tested for the detection of other metal ions too. This work would facilitate the development of highly sensitive POU hand-held sensors for water quality monitoring in resource-limited areas. [ABSTRACT FROM AUTHOR]
Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 140091080
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Enhancing the sensitivity of point-of-use electrochemical microfluidic sensors by ion concentration polarisation – A case study on arsenic.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Subramanian%2C+Vidhya%22">Subramanian, Vidhya</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lee%2C+Sangjun%22">Lee, Sangjun</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jena%2C+Sanjoy%22">Jena, Sanjoy</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jana%2C+Sourav+Kanti%22">Jana, Sourav Kanti</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ray%2C+Debdutta%22">Ray, Debdutta</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Sung+Jae%22">Kim, Sung Jae</searchLink><relatesTo>3,5,6</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Thalappil%2C+Pradeep%22">Thalappil, Pradeep</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> pradeep@iitm.ac.in</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Sensors+%26+Actuators+B%3A+Chemical%22">Sensors & Actuators B: Chemical</searchLink>. Feb2020, Vol. 304, pN.PAG-N.PAG. 1p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Electrochemical+sensors%22">Electrochemical sensors</searchLink><br /><searchLink fieldCode="DE" term="%22Microfluidic+devices%22">Microfluidic devices</searchLink><br /><searchLink fieldCode="DE" term="%22Water+quality+monitoring%22">Water quality monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22Fluidics%22">Fluidics</searchLink><br /><searchLink fieldCode="DE" term="%22Labs+on+a+chip%22">Labs on a chip</searchLink><br /><searchLink fieldCode="DE" term="%22Arsenic%22">Arsenic</searchLink><br /><searchLink fieldCode="DE" term="%22Metal+detectors%22">Metal detectors</searchLink><br /><searchLink fieldCode="DE" term="%22Arsenic+compounds%22">Arsenic compounds</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22India%22">India</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: • First report of utilising Ion Concentration Polarisation for concentrating ions in a microfluidic device. • Facile fabrication technique for the development of multiple layer Lab on a Chip device without the use of valves. • Detection of As3+ to 1 ppb without surface modification of the working electrode. • Detection of 7 ppb of As3+ in field sample without any pre-treatment of the sample. Point of use (POU) sensors are extremely relevant, being capable of providing fast and reliable analysis in remote and resource-limited settings. Of all the diverse techniques utilised for POU sensors, a combination of electrochemistry and microfluidics may have the greatest potential towards quantitative assessment of heavy metal ions. The major challenge in combining these for sensing applications lies in the complexity of fabricating integrated devices and the insufficient quantity of analytes in the sample volume. To address these issues, we have developed a radial microfluidic device capable of electrokinetic preconcentration by ion concentration polarization (ICP) and integrated it with electroactive surfaces. The proposed sensor is the first demonstration of concentration of heavy metal ions by ICP and its quantitative assessment by voltammetry. Utilising the integrated sensor, we have shown the sensing of As3+ down to 1 ppb by linear sweep voltammetry with ∼40 μL of sample. The sensor was also tested successfully for sensing As3+ in a field sample from an arsenic affected region of India. The sensor was also tested for the detection of other metal ions too. This work would facilitate the development of highly sensitive POU hand-held sensors for water quality monitoring in resource-limited areas. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=140091080
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.snb.2019.127340
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: Electrochemical sensors
        Type: general
      – SubjectFull: Microfluidic devices
        Type: general
      – SubjectFull: Water quality monitoring
        Type: general
      – SubjectFull: Fluidics
        Type: general
      – SubjectFull: Labs on a chip
        Type: general
      – SubjectFull: Arsenic
        Type: general
      – SubjectFull: Metal detectors
        Type: general
      – SubjectFull: Arsenic compounds
        Type: general
      – SubjectFull: India
        Type: general
    Titles:
      – TitleFull: Enhancing the sensitivity of point-of-use electrochemical microfluidic sensors by ion concentration polarisation – A case study on arsenic.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Subramanian, Vidhya
      – PersonEntity:
          Name:
            NameFull: Lee, Sangjun
      – PersonEntity:
          Name:
            NameFull: Jena, Sanjoy
      – PersonEntity:
          Name:
            NameFull: Jana, Sourav Kanti
      – PersonEntity:
          Name:
            NameFull: Ray, Debdutta
      – PersonEntity:
          Name:
            NameFull: Kim, Sung Jae
      – PersonEntity:
          Name:
            NameFull: Thalappil, Pradeep
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: Feb2020
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-print
              Value: 09254005
          Numbering:
            – Type: volume
              Value: 304
          Titles:
            – TitleFull: Sensors & Actuators B: Chemical
              Type: main
ResultId 1