View in EDS

Calculation of S-values for head and brain structures from a constructed voxelized phantom for positron-emitting radionuclides.

Saved in:
Bibliographic Details
Title: Calculation of S-values for head and brain structures from a constructed voxelized phantom for positron-emitting radionuclides.
Authors: Reynoso-Mejía, C.A.1,2 (AUTHOR) betoven@ciencias.unam.mx, Kerik-Rotenberg, N.2 (AUTHOR) nora.kerik@hotmail.com, Moranchel, M.1 (AUTHOR) mmoranchel1508@gmail.com
Source: Radiation Physics & Chemistry. Jan2020, Vol. 166, pN.PAG-N.PAG. 1p.
Subjects: International Commission on Radiological Protection, Radioisotopes, Brain, Monte Carlo method, Positrons, Absorbed dose, Head, Positron emission
Abstract: Stylized and voxelized phantoms have been used to estimate S-values for positron-emitting radionuclides. However, there is a lack of computational phantoms that include head and brain structures of importance for neuroimaging studies, such as brain PET-CT. The aim of this work was to construct a multi-resolution whole-body phantom for Monte Carlo simulations in MCNP code that includes a complete set of head and brain structures. The International Commission on Radiological Protection (ICRP-110) male reference phantom and the Zubal head phantom were used to construct the ICRP-HEAD phantom. This multi-resolution phantom was used to calculate self-absorbed fractions (SAFs) and S-values for seven positron-emitting radionuclides used in PET neuroimaging (C-11, O-15, F-18, Cu-64, I-124, Ga-68, and Y-86). S-values calculated in this work were compared with two head/brain phantoms previously published: the stylized MIRD-15 phantom and the tomographic VIP-Man phantom. The voxel resolution of the phantom resulted well suited for Monte Carlo simulations in MCNP6.2 code. For the same target and source structure, the highest auto absorbed S-values were produced by O-15 and Ga-68, while for different target and source structures, Y-86 produced the highest S-values. The lowest S-values were produced by Cu-64. Comparison of S-values with those calculated from the MIRD-15 phantom showed significant differences, while a better agreement was found with those calculated from the VIP-Man phantom. The S-values obtained in this work could help to improve the accuracy of absorbed dose in brain and head structures for positron-emitting radionuclides used in PET neuroimaging. • A multi-resolution whole-body phantom was constructed in MCNP code that include a complete set of head and brain structures. • A voxel phantom was constructed based on the ICRP-110 adult male reference phantom and on the Zubal head phantom. • Self-absorbed fractions (self-AFs) and S-values were calculated for seven positron-emitting radionuclides. • The constructed ICRP-head phantom provides a more accurate representation of the head and brain structures. [ABSTRACT FROM AUTHOR]
Copyright of Radiation Physics & Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 140986029
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Calculation of S-values for head and brain structures from a constructed voxelized phantom for positron-emitting radionuclides.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Reynoso-Mejía%2C+C%2EA%2E%22">Reynoso-Mejía, C.A.</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> betoven@ciencias.unam.mx</i><br /><searchLink fieldCode="AR" term="%22Kerik-Rotenberg%2C+N%2E%22">Kerik-Rotenberg, N.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> nora.kerik@hotmail.com</i><br /><searchLink fieldCode="AR" term="%22Moranchel%2C+M%2E%22">Moranchel, M.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> mmoranchel1508@gmail.com</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Radiation+Physics+%26+Chemistry%22">Radiation Physics & Chemistry</searchLink>. Jan2020, Vol. 166, pN.PAG-N.PAG. 1p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22International+Commission+on+Radiological+Protection%22">International Commission on Radiological Protection</searchLink><br /><searchLink fieldCode="DE" term="%22Radioisotopes%22">Radioisotopes</searchLink><br /><searchLink fieldCode="DE" term="%22Brain%22">Brain</searchLink><br /><searchLink fieldCode="DE" term="%22Monte+Carlo+method%22">Monte Carlo method</searchLink><br /><searchLink fieldCode="DE" term="%22Positrons%22">Positrons</searchLink><br /><searchLink fieldCode="DE" term="%22Absorbed+dose%22">Absorbed dose</searchLink><br /><searchLink fieldCode="DE" term="%22Head%22">Head</searchLink><br /><searchLink fieldCode="DE" term="%22Positron+emission%22">Positron emission</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Stylized and voxelized phantoms have been used to estimate S-values for positron-emitting radionuclides. However, there is a lack of computational phantoms that include head and brain structures of importance for neuroimaging studies, such as brain PET-CT. The aim of this work was to construct a multi-resolution whole-body phantom for Monte Carlo simulations in MCNP code that includes a complete set of head and brain structures. The International Commission on Radiological Protection (ICRP-110) male reference phantom and the Zubal head phantom were used to construct the ICRP-HEAD phantom. This multi-resolution phantom was used to calculate self-absorbed fractions (SAFs) and S-values for seven positron-emitting radionuclides used in PET neuroimaging (C-11, O-15, F-18, Cu-64, I-124, Ga-68, and Y-86). S-values calculated in this work were compared with two head/brain phantoms previously published: the stylized MIRD-15 phantom and the tomographic VIP-Man phantom. The voxel resolution of the phantom resulted well suited for Monte Carlo simulations in MCNP6.2 code. For the same target and source structure, the highest auto absorbed S-values were produced by O-15 and Ga-68, while for different target and source structures, Y-86 produced the highest S-values. The lowest S-values were produced by Cu-64. Comparison of S-values with those calculated from the MIRD-15 phantom showed significant differences, while a better agreement was found with those calculated from the VIP-Man phantom. The S-values obtained in this work could help to improve the accuracy of absorbed dose in brain and head structures for positron-emitting radionuclides used in PET neuroimaging. • A multi-resolution whole-body phantom was constructed in MCNP code that include a complete set of head and brain structures. • A voxel phantom was constructed based on the ICRP-110 adult male reference phantom and on the Zubal head phantom. • Self-absorbed fractions (self-AFs) and S-values were calculated for seven positron-emitting radionuclides. • The constructed ICRP-head phantom provides a more accurate representation of the head and brain structures. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Radiation Physics & Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=140986029
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.radphyschem.2019.108427
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: International Commission on Radiological Protection
        Type: general
      – SubjectFull: Radioisotopes
        Type: general
      – SubjectFull: Brain
        Type: general
      – SubjectFull: Monte Carlo method
        Type: general
      – SubjectFull: Positrons
        Type: general
      – SubjectFull: Absorbed dose
        Type: general
      – SubjectFull: Head
        Type: general
      – SubjectFull: Positron emission
        Type: general
    Titles:
      – TitleFull: Calculation of S-values for head and brain structures from a constructed voxelized phantom for positron-emitting radionuclides.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Reynoso-Mejía, C.A.
      – PersonEntity:
          Name:
            NameFull: Kerik-Rotenberg, N.
      – PersonEntity:
          Name:
            NameFull: Moranchel, M.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: Jan2020
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-print
              Value: 0969806X
          Numbering:
            – Type: volume
              Value: 166
          Titles:
            – TitleFull: Radiation Physics & Chemistry
              Type: main
ResultId 1