Stability testing blister packs inspected with Sepha's VisionScan test method.

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Bibliographic Details
Title:	Stability testing blister packs inspected with Sepha's VisionScan test method.
Authors:	Dixon, D.¹ author.ppp@gmail.com
Source:	Popular Plastics & Packaging. Jan2020, Vol. 65 Issue 1, p32-42. 6p.
Subjects:	Leak detection, Methods engineering, Test systems, Imaging systems
Abstract:	The Sepha VisionScan leak detection system tests the integrity of blister packs using vacuum and vision technologic The method works by creating a vacuum around a blister pack while a high-resolution imaging system monitors changes in the individual blister pockets. Any difference in pocket shape which deviates from the expected behaviour when establishing the vacuum, or during the dwell time of the vacuum, indicates leakage of air from the blister pocket. This is based on the principle in the ASTM standard F3169. A stability study was set up to investigate if the Sepha VisionScan test method impacts the integrity of blister pockets. The study reports on the tablet moisture determination (which will be an indicator of changes in the integrity of the blister) by stability testing blister packs which have been leak tested in the Sepha VisionScan system versus blister packs which have not been leak tested in the VisionScan. The stability study testing is conducted on blisters which are constructed from the following materials PVC/PVdC, PVC/PE/PCTFE (ACLAR), ALU/ALU The study shows there is no significant difference in the integrity of blisters when inspected with the Sepha VisionScan leak detection system compared to blisters not inspected by the system and proves the VisionScan technique is a non-destructive solution to assure package integrity. [ABSTRACT FROM AUTHOR]
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Database:	Engineering Source

Description
Abstract:	The Sepha VisionScan leak detection system tests the integrity of blister packs using vacuum and vision technologic The method works by creating a vacuum around a blister pack while a high-resolution imaging system monitors changes in the individual blister pockets. Any difference in pocket shape which deviates from the expected behaviour when establishing the vacuum, or during the dwell time of the vacuum, indicates leakage of air from the blister pocket. This is based on the principle in the ASTM standard F3169. A stability study was set up to investigate if the Sepha VisionScan test method impacts the integrity of blister pockets. The study reports on the tablet moisture determination (which will be an indicator of changes in the integrity of the blister) by stability testing blister packs which have been leak tested in the Sepha VisionScan system versus blister packs which have not been leak tested in the VisionScan. The stability study testing is conducted on blisters which are constructed from the following materials PVC/PVdC, PVC/PE/PCTFE (ACLAR), ALU/ALU The study shows there is no significant difference in the integrity of blisters when inspected with the Sepha VisionScan leak detection system compared to blisters not inspected by the system and proves the VisionScan technique is a non-destructive solution to assure package integrity. [ABSTRACT FROM AUTHOR]
ISSN:	09710078