View in EDS PDF Full Text

Hyperpolarized 129Xe multi‐slice imaging of the human brain using a 3D gradient echo pulse sequence.

Saved in:
Bibliographic Details
Title: Hyperpolarized 129Xe multi‐slice imaging of the human brain using a 3D gradient echo pulse sequence.
Authors: Grynko, Vira1,2 (AUTHOR), Shepelytskyi, Yurii2,3 (AUTHOR), Li, Tao3 (AUTHOR), Hassan, Ayman4,5 (AUTHOR), Granberg, Karl4 (AUTHOR), Albert, Mitchell S.2,3,5 (AUTHOR) malbert1@lakeheadu.ca
Source: Magnetic Resonance in Medicine. Dec2021, Vol. 86 Issue 6, p3175-3181. 7p.
Subjects: Magnetic resonance imaging, Brain imaging, Gray matter (Nerve tissue), Signal-to-noise ratio
Geographic Terms: Andover (Mass.)
Abstract: Purpose: To demonstrate the possibility of performing multi‐slice in‐vivo human brain MRI using hyperpolarized (HP) xenon‐129 (129Xe) in two different orientations and to calculate the signal‐to‐noise ratio (SNR). Methods: Two healthy female participants were imaged during a single breath‐hold of HP 129Xe using a Philips Achieva 3.0T MRI scanner (Philips, Andover, MA). Each HP 129Xe multi‐slice brain image was acquired during separate HP 129Xe breath‐holds using 3D gradient echo (GRE) imaging. The acquisition started 10 s after the inhalation of 1 L of HP 129Xe. Overall, four sagittal and three axial images were acquired (seven imaging sessions per participant). The SNR was calculated for each slice in both orientations. Results: The first ever HP 129Xe multi‐slice images of the brain were acquired in axial and sagittal orientations. The HP 129Xe signal distribution correlated well with the gray matter distribution. The highest SNR values were close in the axial and sagittal orientations (19.46 ± 3.25 and 18.76 ± 4.94, respectively). Additionally, anatomical features, such as the ventricles, were observed in both orientations. Conclusion: The possibility of using multi‐slice HP 129Xe human brain magnetic resonance imaging was demonstrated for the first time. HP 129Xe multi‐slice MRI can be implemented for brain imaging to improve current diagnostic methods. [ABSTRACT FROM AUTHOR]
Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 153385159
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Hyperpolarized <superscript>129</superscript>Xe multi‐slice imaging of the human brain using a 3D gradient echo pulse sequence.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Grynko%2C+Vira%22">Grynko, Vira</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shepelytskyi%2C+Yurii%22">Shepelytskyi, Yurii</searchLink><relatesTo>2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Tao%22">Li, Tao</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hassan%2C+Ayman%22">Hassan, Ayman</searchLink><relatesTo>4,5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Granberg%2C+Karl%22">Granberg, Karl</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Albert%2C+Mitchell+S%2E%22">Albert, Mitchell S.</searchLink><relatesTo>2,3,5</relatesTo> (AUTHOR)<i> malbert1@lakeheadu.ca</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Dec2021, Vol. 86 Issue 6, p3175-3181. 7p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+imaging%22">Brain imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Gray+matter+%28Nerve+tissue%29%22">Gray matter (Nerve tissue)</searchLink><br /><searchLink fieldCode="DE" term="%22Signal-to-noise+ratio%22">Signal-to-noise ratio</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Andover+%28Mass%2E%29%22">Andover (Mass.)</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: To demonstrate the possibility of performing multi‐slice in‐vivo human brain MRI using hyperpolarized (HP) xenon‐129 (129Xe) in two different orientations and to calculate the signal‐to‐noise ratio (SNR). Methods: Two healthy female participants were imaged during a single breath‐hold of HP 129Xe using a Philips Achieva 3.0T MRI scanner (Philips, Andover, MA). Each HP 129Xe multi‐slice brain image was acquired during separate HP 129Xe breath‐holds using 3D gradient echo (GRE) imaging. The acquisition started 10 s after the inhalation of 1 L of HP 129Xe. Overall, four sagittal and three axial images were acquired (seven imaging sessions per participant). The SNR was calculated for each slice in both orientations. Results: The first ever HP 129Xe multi‐slice images of the brain were acquired in axial and sagittal orientations. The HP 129Xe signal distribution correlated well with the gray matter distribution. The highest SNR values were close in the axial and sagittal orientations (19.46 ± 3.25 and 18.76 ± 4.94, respectively). Additionally, anatomical features, such as the ventricles, were observed in both orientations. Conclusion: The possibility of using multi‐slice HP 129Xe human brain magnetic resonance imaging was demonstrated for the first time. HP 129Xe multi‐slice MRI can be implemented for brain imaging to improve current diagnostic methods. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=153385159
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/mrm.28932
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 3175
    Subjects:
      – SubjectFull: Magnetic resonance imaging
        Type: general
      – SubjectFull: Brain imaging
        Type: general
      – SubjectFull: Gray matter (Nerve tissue)
        Type: general
      – SubjectFull: Signal-to-noise ratio
        Type: general
      – SubjectFull: Andover (Mass.)
        Type: general
    Titles:
      – TitleFull: Hyperpolarized 129Xe multi‐slice imaging of the human brain using a 3D gradient echo pulse sequence.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Grynko, Vira
      – PersonEntity:
          Name:
            NameFull: Shepelytskyi, Yurii
      – PersonEntity:
          Name:
            NameFull: Li, Tao
      – PersonEntity:
          Name:
            NameFull: Hassan, Ayman
      – PersonEntity:
          Name:
            NameFull: Granberg, Karl
      – PersonEntity:
          Name:
            NameFull: Albert, Mitchell S.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 12
              Text: Dec2021
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 07403194
          Numbering:
            – Type: volume
              Value: 86
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: Magnetic Resonance in Medicine
              Type: main
ResultId 1