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Bone fracture healing within a continuum bone remodelling framework.

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Title: Bone fracture healing within a continuum bone remodelling framework.
Authors: Schmidt, Ina1 (AUTHOR), Albert, Jacob2 (AUTHOR), Ritthaler, Marina1 (AUTHOR), Papastavrou, Areti1 (AUTHOR), Steinmann, Paul2 (AUTHOR)
Source: Computer Methods in Biomechanics & Biomedical Engineering. Jul2022, Vol. 25 Issue 9, p1040-1050. 11p.
Subjects: Fracture healing, Bone remodeling, Bone fractures, Femur head, Bone growth, Femur, Healing
Abstract: Bone fracture healing is a complex process which is still under research. Computer-aided patient-specific prediction of bone development, fracture risk, prevention and treatment approaches promises a significant milestone in clinical practice. With this long-term goal in mind, a novel model is presented and examined in this work in the context of continuum bone remodelling. Therein, a clear distinction is made between external mechanical stimulation and the biological healing process of an injured bone tissue. The model is implemented within a finite element framework and investigated for the example of a fractured proximal femur head. The results show promising perspectives for further application. Besides, the model offers the possibility of easily integrating other factors like age-dependency and the availability of nutrition. For the future, further studies with large clinical datasets are essential for validation. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
Description
Abstract:Bone fracture healing is a complex process which is still under research. Computer-aided patient-specific prediction of bone development, fracture risk, prevention and treatment approaches promises a significant milestone in clinical practice. With this long-term goal in mind, a novel model is presented and examined in this work in the context of continuum bone remodelling. Therein, a clear distinction is made between external mechanical stimulation and the biological healing process of an injured bone tissue. The model is implemented within a finite element framework and investigated for the example of a fractured proximal femur head. The results show promising perspectives for further application. Besides, the model offers the possibility of easily integrating other factors like age-dependency and the availability of nutrition. For the future, further studies with large clinical datasets are essential for validation. [ABSTRACT FROM AUTHOR]
ISSN:10255842
DOI:10.1080/10255842.2021.1998465