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Through the looking-glass - Recent developments in reflectometry open new possibilities for biosensor applications.

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Title: Through the looking-glass - Recent developments in reflectometry open new possibilities for biosensor applications.
Authors: Fechner, Peter1 (AUTHOR) peter.fechner@uni-tuebingen.de, Gauglitz, Günter1 (AUTHOR), Proll, Günther1 (AUTHOR)
Source: Trends in Analytical Chemistry: TRAC. Nov2022, Vol. 156, pN.PAG-N.PAG. 1p.
Subjects: Reflectometry, Biosensors, Spectral reflectance, Art techniques, Spectral imaging, Interferometry
Abstract: Label-free biosensing has developed from niche application to state of the art biosensing technique throughout the past decades. The reason for the raise of acceptance for this technology is the fact, that it generates valuable kinetic data (on- and off-rates), does not require complicated sample-pre-treatment, and can be used in direct test formats. As the acceptance increased, label-free advanced and many different approaches with the same underlying principles have evolved. This review will take a brief look at the history, and explore the reflectometry family tree, which includes ellipsometry as the main ancestor, Reflectometric Interference Spectroscopy (RIfS), Biolayer Interferometry (BLI), Total Reflectometric Interference Spectroscopy (TRIS), Spectral Reflectance Imaging Biosensor (SRIB or also IRIS), 1ʎ Reflectometry, Arrayed Imaging Reflectometry (AIR), and Oblique-Incidence Reflectivity Difference microscopy (OI-RD) and highlight extraordinary examples of recent developments and their impact in biomolecular interaction analysis. • Reflectometric biosensing has evolved over the years. • High throughput is one of the key advantages of reflectometry compared the refractometry. • Complex biological questions can be answered with reflectometry. • New materials enhance the power of reflectometry. [ABSTRACT FROM AUTHOR]
Copyright of Trends in Analytical Chemistry: TRAC is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 159435175
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Through the looking-glass - Recent developments in reflectometry open new possibilities for biosensor applications.
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  Data: <searchLink fieldCode="AR" term="%22Fechner%2C+Peter%22">Fechner, Peter</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> peter.fechner@uni-tuebingen.de</i><br /><searchLink fieldCode="AR" term="%22Gauglitz%2C+Günter%22">Gauglitz, Günter</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Proll%2C+Günther%22">Proll, Günther</searchLink><relatesTo>1</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Trends+in+Analytical+Chemistry%3A+TRAC%22">Trends in Analytical Chemistry: TRAC</searchLink>. Nov2022, Vol. 156, pN.PAG-N.PAG. 1p.
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  Data: <searchLink fieldCode="DE" term="%22Reflectometry%22">Reflectometry</searchLink><br /><searchLink fieldCode="DE" term="%22Biosensors%22">Biosensors</searchLink><br /><searchLink fieldCode="DE" term="%22Spectral+reflectance%22">Spectral reflectance</searchLink><br /><searchLink fieldCode="DE" term="%22Art+techniques%22">Art techniques</searchLink><br /><searchLink fieldCode="DE" term="%22Spectral+imaging%22">Spectral imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Interferometry%22">Interferometry</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Label-free biosensing has developed from niche application to state of the art biosensing technique throughout the past decades. The reason for the raise of acceptance for this technology is the fact, that it generates valuable kinetic data (on- and off-rates), does not require complicated sample-pre-treatment, and can be used in direct test formats. As the acceptance increased, label-free advanced and many different approaches with the same underlying principles have evolved. This review will take a brief look at the history, and explore the reflectometry family tree, which includes ellipsometry as the main ancestor, Reflectometric Interference Spectroscopy (RIfS), Biolayer Interferometry (BLI), Total Reflectometric Interference Spectroscopy (TRIS), Spectral Reflectance Imaging Biosensor (SRIB or also IRIS), 1ʎ Reflectometry, Arrayed Imaging Reflectometry (AIR), and Oblique-Incidence Reflectivity Difference microscopy (OI-RD) and highlight extraordinary examples of recent developments and their impact in biomolecular interaction analysis. • Reflectometric biosensing has evolved over the years. • High throughput is one of the key advantages of reflectometry compared the refractometry. • Complex biological questions can be answered with reflectometry. • New materials enhance the power of reflectometry. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Trends in Analytical Chemistry: TRAC is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=159435175
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        Value: 10.1016/j.trac.2022.116708
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      – Code: eng
        Text: English
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      – SubjectFull: Reflectometry
        Type: general
      – SubjectFull: Biosensors
        Type: general
      – SubjectFull: Spectral reflectance
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      – SubjectFull: Art techniques
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      – SubjectFull: Spectral imaging
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      – SubjectFull: Interferometry
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      – TitleFull: Through the looking-glass - Recent developments in reflectometry open new possibilities for biosensor applications.
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            NameFull: Gauglitz, Günter
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            – D: 01
              M: 11
              Text: Nov2022
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