Cell‐free protein synthesis system: A new frontier for sustainable biotechnology‐based products.
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| Title: | Cell‐free protein synthesis system: A new frontier for sustainable biotechnology‐based products. |
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| Authors: | Maharjan, Anoth1 (AUTHOR), Park, Jung‐Ho1,2 (AUTHOR) jungho@kribb.re.kr |
| Source: | Biotechnology & Applied Biochemistry. Dec2023, Vol. 70 Issue 6, p2136-2149. 14p. |
| Subjects: | Protein synthesis, Technological innovations, Synthetic biology, Biomolecules |
| Abstract: | Cell‐free protein synthesis (CFPS) system is an innovative technology with a wide range of potential applications that could challenge current thinking and provide solutions to environmental and health issues. CFPS system has been demonstrated to be a successful way of producing biomolecules in a variety of applications, including the biomedical industry. Although there are still obstacles to overcome, its ease of use, versatility, and capacity for integration with other technologies open the door for it to continue serving as a vital instrument in synthetic biology research and industry. In this review, we mainly focus on the cell‐free based platform for various product productions. Moreover, the challenges in the bio‐therapeutic aspect using cell‐free systems and their future prospective for the improvement and sustainability of the cell free systems. [ABSTRACT FROM AUTHOR] |
| Copyright of Biotechnology & Applied Biochemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Abstract: | Cell‐free protein synthesis (CFPS) system is an innovative technology with a wide range of potential applications that could challenge current thinking and provide solutions to environmental and health issues. CFPS system has been demonstrated to be a successful way of producing biomolecules in a variety of applications, including the biomedical industry. Although there are still obstacles to overcome, its ease of use, versatility, and capacity for integration with other technologies open the door for it to continue serving as a vital instrument in synthetic biology research and industry. In this review, we mainly focus on the cell‐free based platform for various product productions. Moreover, the challenges in the bio‐therapeutic aspect using cell‐free systems and their future prospective for the improvement and sustainability of the cell free systems. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 08854513 |
| DOI: | 10.1002/bab.2514 |
