The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology.
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| Title: | The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology. |
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| Authors: | Kim, Kyu Jae1 (AUTHOR), Lee, So-Jeong1 (AUTHOR), Kim, Dong-Myung1 (AUTHOR) dmkim@cnu.ac.kr |
| Source: | Biotechnology & Bioprocess Engineering. Dec2023, Vol. 28 Issue 6, p922-928. 7p. |
| Subjects: | Protein synthesis, Synthetic biology, Biological systems, Green business, Artificial cells, Recombinant proteins |
| Abstract: | Cell-free protein synthesis is emerging as a powerful tool to accelerate the progress of synthetic biology. Notably, cell-free systems that harness extracted synthetic machinery of cells can address many of the issues associated with the complexity and variability of living systems. In particular, cell-free systems can be programmed with various configurations of genetic information, providing great flexibility and accessibility to the field of synthetic biology. Empowered by recent progress, cell-free systems are now evolving into artificial biological systems that can be tailored for various applications, including on-demand biomanufacturing, diagnostics, and new materials design. Here, we review the key developments related to cell-free protein synthesis systems, and discuss the future directions of these promising technologies. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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