Reproducibility of Time and Frequency Domain Analysis of Heart Rate Variability in Patients with Chronic Stable Angina.

Saved in:

Bibliographic Details
Title:	Reproducibility of Time and Frequency Domain Analysis of Heart Rate Variability in Patients with Chronic Stable Angina.
Authors:	Kamalesh, Masoor¹, Burger, Andrew J.¹, Kumar, Shylendra¹, Nesto, Richard¹
Source:	Pacing & Clinical Electrophysiology. Nov1995, Vol. 18 Issue 11, p1991-1994. 4p.
Subjects:	Heart beat, Angina pectoris, Drugs, Ambulatory electrocardiography, Patients, Therapeutics
Abstract:	Before heart rate variability (HRV) can be used to investigate the effects of drugs or other clinical interventions in chronic stable angina, it is important to establish the stability and reproducibility of HRV indices overtime. HRV analysis was performed on two consecutive 24-hour ambulatory EGG recordings in 19 patients with chronic stable angina. Time-domain analysis included average heart rate, variance, SDNN, SDANN5, ASDNN5, and PNN50. The power spectral analysis was computed using fast Fourier transformation for the total power (0.003 and 0.40 Hz), low frequency (0.04-0.15 Hz), and high frequency (0.15-0.40 Hz) bands. No statistically significant differences in the time or frequency domains were found between the two ambulatory EGG recordings. HRV indices in the time and frequency domains are consistent and reproducible in patients with chronic stable angina. Thus, cardiac autonomic tone can be evaluated using HRV analyses, and any significant changes that occur after medical therapy or other clinical interventions can be ascribed to the intervention rather than the lability of cardiac autonomic tone. [ABSTRACT FROM AUTHOR]
	Copyright of Pacing & Clinical Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database:	Engineering Source

Description
Abstract:	Before heart rate variability (HRV) can be used to investigate the effects of drugs or other clinical interventions in chronic stable angina, it is important to establish the stability and reproducibility of HRV indices overtime. HRV analysis was performed on two consecutive 24-hour ambulatory EGG recordings in 19 patients with chronic stable angina. Time-domain analysis included average heart rate, variance, SDNN, SDANN5, ASDNN5, and PNN50. The power spectral analysis was computed using fast Fourier transformation for the total power (0.003 and 0.40 Hz), low frequency (0.04-0.15 Hz), and high frequency (0.15-0.40 Hz) bands. No statistically significant differences in the time or frequency domains were found between the two ambulatory EGG recordings. HRV indices in the time and frequency domains are consistent and reproducible in patients with chronic stable angina. Thus, cardiac autonomic tone can be evaluated using HRV analyses, and any significant changes that occur after medical therapy or other clinical interventions can be ascribed to the intervention rather than the lability of cardiac autonomic tone. [ABSTRACT FROM AUTHOR]
ISSN:	01478389
DOI:	10.1111/j.1540-8159.1995.tb03858.x