The Effect of Low-Dose CT Protocols on Shoulder Model-Based Tracking accuracy Using Biplane Videoradiography.

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Title: The Effect of Low-Dose CT Protocols on Shoulder Model-Based Tracking accuracy Using Biplane Videoradiography.
Authors: Chen, Stacey1 (AUTHOR), Lee, Erin C. S.2 (AUTHOR), Napier, Kelby B.3 (AUTHOR), Rainbow, Michael J.2 (AUTHOR) michael.rainbow@queensu.ca, Lawrence, Rebekah L.1 (AUTHOR) r.lawrence@wustl.edu
Source: Annals of Biomedical Engineering. Feb2025, Vol. 53 Issue 2, p481-491. 11p.
Subjects: Medical sciences, Motion analysis, Computed tomography, Clavicle, Torso, Shoulder, Radiation exposure
Abstract: Purpose: Model-based tracking is being increasingly used to quantify shoulder kinematics and typically employs computed tomography (CT) to create the 3D bone volumes, which adds to the total radiation exposure. Lower-dose CT protocols may be possible given the contrast between bone and the surrounding soft tissues. The purpose of this study was to describe the dose-accuracy tradeoff between low-dose CT scans and the kinematic tracking accuracy of the humerus, scapula, and clavicle when tracked using an intensity-based registration algorithm. Methods: Three fresh-frozen cadavers consisting of the torso and bilateral shoulders were tested. The CT protocols investigated included a full-dose protocol and 4 experimental low-dose protocols that modulated x-ray tube current and peak voltage. Bead-based tracking (i.e., radiostereometric analysis) served as the reference standard to which model-based tracking results were compared. Accuracy was described in terms of both segmental (humerus, scapula, and clavicle) and joint (glenohumeral, acromioclavicular) kinematics using root-mean-square (RMSE), bias, precision, and worst-case errors. Results: The low-dose CT scans resulted in an average dose reduction of 70.6–92.8%. RMSEs tended to increase as CT dose decreased with average glenohumeral errors increasing from 0.5° and 0.6 mm to 0.6° and 0.6 mm between the highest and lowest-dose protocols, and average acromioclavicular errors increasing from 0.6° and 0.8 mm to 0.7° and 0.9 mm. However, the difference in joint kinematic errors between the highest and lowest-dose CT scanning protocols was generally small (≤0.3°, ≤ 0.1 mm). Conclusion: It is possible to substantially reduce the CT dose associated with shoulder motion analysis using biplane videoradiography without significantly impacting data fidelity. [ABSTRACT FROM AUTHOR]
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Abstract:Purpose: Model-based tracking is being increasingly used to quantify shoulder kinematics and typically employs computed tomography (CT) to create the 3D bone volumes, which adds to the total radiation exposure. Lower-dose CT protocols may be possible given the contrast between bone and the surrounding soft tissues. The purpose of this study was to describe the dose-accuracy tradeoff between low-dose CT scans and the kinematic tracking accuracy of the humerus, scapula, and clavicle when tracked using an intensity-based registration algorithm. Methods: Three fresh-frozen cadavers consisting of the torso and bilateral shoulders were tested. The CT protocols investigated included a full-dose protocol and 4 experimental low-dose protocols that modulated x-ray tube current and peak voltage. Bead-based tracking (i.e., radiostereometric analysis) served as the reference standard to which model-based tracking results were compared. Accuracy was described in terms of both segmental (humerus, scapula, and clavicle) and joint (glenohumeral, acromioclavicular) kinematics using root-mean-square (RMSE), bias, precision, and worst-case errors. Results: The low-dose CT scans resulted in an average dose reduction of 70.6–92.8%. RMSEs tended to increase as CT dose decreased with average glenohumeral errors increasing from 0.5° and 0.6 mm to 0.6° and 0.6 mm between the highest and lowest-dose protocols, and average acromioclavicular errors increasing from 0.6° and 0.8 mm to 0.7° and 0.9 mm. However, the difference in joint kinematic errors between the highest and lowest-dose CT scanning protocols was generally small (≤0.3°, ≤ 0.1 mm). Conclusion: It is possible to substantially reduce the CT dose associated with shoulder motion analysis using biplane videoradiography without significantly impacting data fidelity. [ABSTRACT FROM AUTHOR]
ISSN:00906964
DOI:10.1007/s10439-024-03645-3