Bleaching efficacy and tooth sensitivity using violet LED – single-blind randomized controlled trial.

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Title: Bleaching efficacy and tooth sensitivity using violet LED – single-blind randomized controlled trial.
Authors: Zanin, Gabriela Torres1,2 (AUTHOR) gabrielatorreszanin@gmail.com, Ribeiro, Edgar Pedreiro1,2 (AUTHOR) edgarribeiro22@gmail.com, Maran, Bianca Medeiros3,4 (AUTHOR) medeiros.bianca@hotmail.com, Lopes, Murilo Baena1,2 (AUTHOR) baenalopes@gmail.com, Guiraldo, Ricardo Danil1,2 (AUTHOR) rdguiraldo@gmail.com, Reis, Alessandra5 (AUTHOR) reis_ale@hotmail.com, Loguercio, Alessandro D.5 (AUTHOR) aloguercio@hotmail.com, Berger, Sandrine Bittencourt1,2 (AUTHOR) berger.sandrine@gmail.com
Source: Lasers in Medical Science. 5/19/2025, Vol. 40 Issue 1, p1-9. 9p.
Subjects: Tooth sensitivity, Tooth whitening, Randomized controlled trials, Fisher exact test, Hydrogen peroxide
Abstract: This study aims to conduct a single-blind randomized controlled trial to evaluate the bleaching efficacy and tooth sensitivity (TS) following the use of violet LED associated or not with 35% hydrogen peroxide. Eighty-four participants were randomly allocated into three groups according to bleaching treatments (n = 28): 35% hydrogen peroxide (HP) only, Violet LED only (VLED), and an association of 35% HP with violet LED (HP + VLED). Three sessions were performed, with an interval of seven days between each one. Changes in the objective (ΔEab and ΔE00) and subjective (ΔSGU) color and the Whiteness Index for Dentistry (ΔWID) were calculated based on before, and seven and thirty days after treatment using colorimetric measurements. Participants self-reported the risk and intensity of TS on a visual analogue scale (VAS). The color assessments seven and 30 days after bleaching were analyzed by two-way ANOVA and Tukey's test. The absolute TS risk was analyzed by Fisher's exact test. The significance level adopted was α = 0.05. HP and HP + VLED treatments showed higher and significant bleaching values (ΔEab, ΔE00, ΔSGU, and ΔWID) compared to VLED. The HP + VLED and HP groups presented a higher risk and intensity of TS compared to the VLED group (p < 0.05). The bleaching efficacy of VLED alone was lower compared to the HP and HP + VLED protocols both seven and 30 days after the end of treatments. [ABSTRACT FROM AUTHOR]
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Abstract:This study aims to conduct a single-blind randomized controlled trial to evaluate the bleaching efficacy and tooth sensitivity (TS) following the use of violet LED associated or not with 35% hydrogen peroxide. Eighty-four participants were randomly allocated into three groups according to bleaching treatments (n = 28): 35% hydrogen peroxide (HP) only, Violet LED only (VLED), and an association of 35% HP with violet LED (HP + VLED). Three sessions were performed, with an interval of seven days between each one. Changes in the objective (ΔEab and ΔE00) and subjective (ΔSGU) color and the Whiteness Index for Dentistry (ΔWID) were calculated based on before, and seven and thirty days after treatment using colorimetric measurements. Participants self-reported the risk and intensity of TS on a visual analogue scale (VAS). The color assessments seven and 30 days after bleaching were analyzed by two-way ANOVA and Tukey's test. The absolute TS risk was analyzed by Fisher's exact test. The significance level adopted was α = 0.05. HP and HP + VLED treatments showed higher and significant bleaching values (ΔEab, ΔE00, ΔSGU, and ΔWID) compared to VLED. The HP + VLED and HP groups presented a higher risk and intensity of TS compared to the VLED group (p < 0.05). The bleaching efficacy of VLED alone was lower compared to the HP and HP + VLED protocols both seven and 30 days after the end of treatments. [ABSTRACT FROM AUTHOR]
ISSN:02688921
DOI:10.1007/s10103-025-04486-9