Effect of Calcium Chloride on Chitosan Behavior in an Acidic Water Mixture for Pharmaceutical and Biomedical Applications.

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Title: Effect of Calcium Chloride on Chitosan Behavior in an Acidic Water Mixture for Pharmaceutical and Biomedical Applications.
Authors: Chikhaoui, Eya1 (AUTHOR), Cherif, Emna1 (AUTHOR) amna_cherif@yahoo.fr
Source: Journal of Macromolecular Science: Physics. 2025, Vol. 64 Issue 8, p968-982. 15p.
Subjects: Molecular size, Dynamic viscosity, Rheology, Drug delivery systems, Biopolymers, Biomaterials
Abstract: The present article reviews the uses of the biopolymer chitosan (CH) and its derivatives as versatile biomaterials for potential drug delivery systems, as well as for tissue engineering applications, analgesia and treatment of arthritis. CH and its derivatives, as natural antimicrobial agents, can be applied in biomedical, biotechnological, and pharmaceutical applications. Its antimicrobial activity depends on many factors, such as its molecular size, source, associated components, concentration and type of microorganism. In addition, in our research described here, we prepared and characterized the dynamic viscosity and the rheological properties of a biopolymer material based on CH/CaCl2 in solution. The dynamic viscosity and shear stress were measured under the influence of an increasing CH concentration of 1 to 10 g/l and an increasing temperature of 288.15 to 318.15 K. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
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Abstract:The present article reviews the uses of the biopolymer chitosan (CH) and its derivatives as versatile biomaterials for potential drug delivery systems, as well as for tissue engineering applications, analgesia and treatment of arthritis. CH and its derivatives, as natural antimicrobial agents, can be applied in biomedical, biotechnological, and pharmaceutical applications. Its antimicrobial activity depends on many factors, such as its molecular size, source, associated components, concentration and type of microorganism. In addition, in our research described here, we prepared and characterized the dynamic viscosity and the rheological properties of a biopolymer material based on CH/CaCl2 in solution. The dynamic viscosity and shear stress were measured under the influence of an increasing CH concentration of 1 to 10 g/l and an increasing temperature of 288.15 to 318.15 K. [ABSTRACT FROM AUTHOR]
ISSN:00222348
DOI:10.1080/00222348.2024.2372979