Reconsidering gadolinium in long-term glioma follow-up: is contrast always and unquestionably necessary?
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| Title: | Reconsidering gadolinium in long-term glioma follow-up: is contrast always and unquestionably necessary? |
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| Authors: | Naval-Baudin, Pablo1,2,3,4 (AUTHOR) pablo.naval.idi@gencat.cat, Pons-Escoda, Albert1,2,3,5 (AUTHOR) |
| Source: | European Radiology. Sep2025, Vol. 35 Issue 9, p5203-5205. 3p. |
| Subjects: | Gadolinium, Gliomas, Magnetic resonance imaging, Imaging systems, Diagnostic imaging, Tumor growth |
| Abstract: | The article discusses the evolving standards for monitoring adult-type diffuse gliomas using MRI, particularly the reliance on gadolinium-enhanced T1-weighted sequences (CET1w) versus non-contrast T2-weighted/FLAIR sequences. Recent findings from a multicenter study suggest that T2w/FLAIR abnormalities can effectively detect tumor progression, often earlier than gadolinium enhancement, raising questions about the necessity of gadolinium in certain cases, especially for long-term survivors of low-grade gliomas. The authors advocate for a balanced approach that utilizes T2w/FLAIR as an initial assessment tool, reserving gadolinium for cases where abnormalities are detected, thereby addressing concerns about gadolinium's safety, cost, and environmental impact. The article emphasizes the need for further research to refine imaging protocols and explore advanced non-contrast techniques in glioma management. [Extracted from the article] |
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| Database: | Engineering Source |
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| Abstract: | The article discusses the evolving standards for monitoring adult-type diffuse gliomas using MRI, particularly the reliance on gadolinium-enhanced T1-weighted sequences (CET1w) versus non-contrast T2-weighted/FLAIR sequences. Recent findings from a multicenter study suggest that T2w/FLAIR abnormalities can effectively detect tumor progression, often earlier than gadolinium enhancement, raising questions about the necessity of gadolinium in certain cases, especially for long-term survivors of low-grade gliomas. The authors advocate for a balanced approach that utilizes T2w/FLAIR as an initial assessment tool, reserving gadolinium for cases where abnormalities are detected, thereby addressing concerns about gadolinium's safety, cost, and environmental impact. The article emphasizes the need for further research to refine imaging protocols and explore advanced non-contrast techniques in glioma management. [Extracted from the article] |
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| ISSN: | 09387994 |
| DOI: | 10.1007/s00330-025-11504-5 |
